In the lively backdrop of 1960s Washington Square Park, a group of spirited hippies gathers to express their beliefs through protest songs and messages of rebellion. Among the lively crowd is Fritz, a charismatic tabby cat with a boundless thirst for adventure and romance. Joined by his fellow feline friends, they embark on a daring quest to impress the ladies. As they serenade passersby, their music initially meets indifference—until the arrival of a trio of enchanting young women who catch their eye, drawn in by a majestic crow perched nearby.
The women's dismissive remarks about people of color are sharply rebutted by the crow, which then takes flight. Unfazed, Fritz takes this as his chance to present himself as a misunderstood soul, convincing the girls that they will discover truth and enlightenment in his presence. The quartet makes its way to a friend's apartment, where a raucous party is already underway.
As the evening progresses, the group becomes engulfed in the celebrations, with Fritz rallying the girls to join him in a wild escapade involving a bathtub. As the festivities ramp up, two heavyset NYPD officers arrive to disrupt the party, but the attendees cleverly evade their attempts to impose order. One officer stumbles upon Fritz and his newfound companions engaged in a passionate rendezvous, prompting chaos as they scramble for cover in a cloud of marijuana smoke.
Despite the officers' pursuit, Fritz rises to the occasion. In a bold act of defiance, he emerges from his haze, seizes one officer's gun, and fires a shot that disrupts the party dramatically—causing the water main to burst, leading to a chaotic rush of partygoers fleeing in all directions.
As the officers pursue him into the streets, Fritz finds himself amidst a synagogue, where the congregation celebrates America's decision to bolster military aid to Israel. Seizing a moment of distraction, Fritz vanishes into the crowd like a ghost.
Upon returning to his dormitory, he discovers his roommates are too absorbed in their studies to notice him. Dissatisfied with the monotony of student life, he takes drastic measures by torching his notes and books, igniting a fire that spreads rapidly, engulfing the entire building. Meanwhile, in the bustling nightlife of Harlem, Fritz encounters Duke the Crow at a pool table, engaging in a high-stakes game. After narrowly escaping trouble with the bartender, Duke encourages Fritz to "bug out," leading them on a reckless vehicle ride that ends with Fritz careening off a bridge—only for Duke to save him at the last second.
The duo soon finds themselves at the apartment of a notorious drug dealer, Bertha, whose potent cannabis heightens Fritz's desires. As they indulge in a passionate encounter, Fritz suddenly feels an urge to spread the revolutionary spirit to the world. Leaving Bertha behind, he steps onto the city streets to incite a riot that escalates dramatically, prompting police and the NY Air National Guard to deploy troops. The chaos culminates in a terrifying moment as F-104 jets drop bombs over Harlem.
Fritz takes refuge in an alley, where he reunites with his older fox girlfriend, Winston Schwartz, who instinctively drags him on a road trip to San Francisco. When their vehicle runs out of fuel in the desert, Fritz abandons her and continues alone. His journey leads him to cross paths with Blue, a drug-addled rabbit biker and his horse girlfriend Harriet. Together, they arrive at an underground hideout where two revolutionaries—a mysterious gecko known as "the lizard leader" and a hooded snake named John—reveal a plot to blow up a power station. Tension escalates when Harriet encourages Blue to join her for a meal, but he responds with violence, compelling Fritz to intervene. However, he is overpowered, resulting in a harrowing scene of betrayal and aggression, culminating in a horrific assault on Harriet.
Later, Fritz has a change of heart regarding the planned destruction and attempts to dismantle the explosives, yet he finds himself caught in the devastating aftermath of the explosion.
In the solemn atmosphere of a Los Angeles hospital, Harriet, disguised as a nun, along with her youthful companions from the park, gather to honor the gravely ill Fritz. Hope seems dim until, unexpectedly, Fritz makes a remarkable recovery. Recalling his earlier charm, he delivers the same passionate speech that once enamored the New York trio. This sparks an impromptu celebration, catching Harriet off guard as Fritz finds himself caught up in another unexpected romantic escapade.
As the hospital's tranquil air shatters, a deputy from the Los Angeles County Sheriff's Department stands guard outside, his serious demeanor betraying a glimmer of respect as he remarks, >"Ah, poor cat... he was a tough kid, wasn't he?" The film concludes with a poignant reminder of a life fully lived, echoed in the bittersweet farewell of those left behind.
