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Dr. Carl Stoner, a herpetologist obsessed with reptiles, makes a clandestine sale of a mysterious creature to a carnival owner. This deal is shrouded in secrecy, highlighting Stoner's hidden motives and obsession.

Stoner recruits college student David Blake as an assistant under the pretense that his former colleague is unavailable due to an emergency. This seemingly innocent arrangement uncovers a dark path as Stoner's mind unravels.

Stoner starts giving David injections, claiming they are safeguards against snake bites in their lab. Unknown to David, these injections are part of Stoner's twisted experiment, revealing the depths of Stoner's delusion.

David begins to undergo a horrifying transformation as his skin starts to resemble that of a snake, losing its humanity. His physical and mental health decline rapidly, but Stoner dismisses it as side effects from the venom.

Despite Stoner's warnings, David develops a romantic relationship with Kristina, his assistant's daughter. Their bond grows deeper even as external dangers loom, complicating the already chaotic situation.

As David continues to receive injections, his skin turns a disturbing greenish hue, resembling scales. This alarming change signifies his losing battle against the transformation orchestrated by Stoner's harmful treatment.

One night, David awakens to a shocking realization: his reflection is monstrous and alien. In panic, he screams, and Stoner quickly intervenes, administering another injection to control the chaos.

Dr. Daniels arrives at the lab, suspicious of Stoner’s activities. Stoner's desperate attempt to hide David leads to a violent confrontation when David reveals his grotesque appearance, escalating the tension.

In a frantic act to cover his crimes, Stoner attacks Dr. Daniels, knocking him unconscious before feeding him to a python. This shocking moment exemplifies the lengths Stoner will go to protect his twisted experiment.

Kristina encounters a freak show featuring a 'snake-man' who bears a chilling resemblance to David. Overcome with horror, she rushes home, desperate to save her beloved from his disturbing fate.

Tragically, Stoner meets his end as he is bitten by a live king cobra in the lab. This act of poetic justice underscores the consequences of his reckless obsession with reptiles and his cruelty towards David.

Upon finding her father dead with the snake coiled nearby, Kristina immediately seeks to alert the authorities. This sense of urgency builds as the realization dawns that something is terribly wrong.

The police arrive just in time to confront the unfolding chaos, shooting the serpent that threatens the lab. In the midst of this, David is attacked by a mongoose, adding another layer of danger.

As the officers hesitate on how to deal with the escalating situation, Kristina calls out for David in desperation. This moment of emotional turmoil encapsulates the tragic climax of their journey.

The film concludes abruptly, leaving the fates of Kristina and David uncertain and shrouded in mystery. This open-ended finale invites viewers to ponder the devastating consequences of obsession and transformation.