The Fabulous Four

Lou and Marilyn meet during their college years, developing a deep and unbreakable bond characterized by infectious laughter and late-night chats. Their friendship becomes a vital foundation that they carry into adulthood.

Transitioning into adulthood, Lou and Marilyn move into a cozy apartment together where they welcome their two new friends, Alice and Kitty. This formation of the Fabulous Four solidifies their shared lives with each friend's unique contributions.

Decades later, Lou has become a respected surgeon, while Kitty has shifted from a biologist to running a flourishing marijuana farm, embracing an 'earth mother' lifestyle. Meanwhile, Alice continues to live extravagantly, holding onto her rock star persona.

Marilyn grapples with an emotional void after the recent loss of her husband, John, with whom she spent 48 years. Seeking solace, she dives deep into the fast-paced world of TikTok, trying to navigate her grief.

In an unexpected turn, Marilyn announces her engagement to be married within a week, shocking her friends. This news prompts her to reach out to Lou, Alice, and Kitty, asking them to be her bridesmaids.

Kitty and Alice formulate a cunning plan to lure Lou back into their friendship fold. They concoct a story about a raffle for a polydactyl cat at the famed Hemingway mansion, knowing Lou's love for cats will be irresistible.

Once at the Hemingway mansion in Florida, Lou confronts Marilyn, leading to emotional tensions as Lou feels betrayed. This confrontation reopens old wounds and unresolved issues between the friends.

In a humorous yet awkward moment, Marilyn gifts Lou a cheeky sex toy as a way to lighten the mood amidst tensions. This occurs during a fashion outing, only amplifying the discontent brewing within Lou.

While shopping for wedding dresses, tensions escalate when Marilyn announces her elopement with John, causing Lou to storm out. This explosive moment leads to an accidental collision with a cyclist, throwing Lou into unexpected circumstances.

Marilyn arranges a thrilling parasailing trip, but Lou's seasickness complicates the fun. Alice tries to cheer Lou up by offering her marijuana-infused chocolate, leading to a mind-bending experience for Lou on the boat.

At Marilyn's bachelorette party at a strip club, a performer named Nathan reveals he is Kitty's grandson. This heartfelt moment fosters joy and acceptance, showcasing the support Kitty provides to the younger generation.

The next day, Marilyn introduces her fiancé, Bradley, who is coincidentally connected to Lou through a cycling accident. This revelation sparks intense conflict between Marilyn and Lou, with emotions running high.

As the wedding day arrives, Marilyn faces a mental breakdown due to the pressure of her whirlwind romance. This culminates in a mutual decision between her and Bradley to separate but remain friends.

Throughout the storyline, Alice often disappears and reappears, taking on a mysterious role. Her sporadic appearances add an air of intrigue as she navigates the unfolding drama of the group's journey.

In the film's conclusion, Kitty delivers a vibrant performance that captivates everyone present. With encouragement from Captain Ernie, Lou decides to embrace her fresh start and leave their chaotic journey behind, looking towards Key West.