Antidote

Antidote

Year: 1000

Runtime: 234 mins

Language: Chinese

ComedyAnimation

After leaving his previous job to pursue art, Cheng Ke, who has never met Jiang Yu, moves in as his tenant and starts a fresh chapter. Though they come from different professions and initially clash with disdain, their hard work and perseverance turn the rivalry into understanding, leading both to achieve success and aim for a brighter future.

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Antidote (1000) – Full Plot Summary & Ending Explained

Read the complete plot breakdown of Antidote (1000), including all key story events, major twists, and the ending explained in detail. Discover what really happened—and what it all means.

Sharyn Berkley is rushed to the hospital by her husband after a sudden, severe pain in the abdomen, where doctors diagnose acute appendicitis and decide on emergency surgery. When she regains consciousness, she meets Dr. Aaron Hellenbach, who reveals that the facility uses unconventional healing methods. Confused by a nearly fully healed surgical incision, Sharyn tries to understand what’s happening, but she flees her room and only catches a fleeting glimpse of Rizzo before the staff sedate her again.

Locked in isolation, Sharyn starts exchanging notes with her neighbor Everett through a small hole in the wall. She witnesses a man with a disturbing bleeding gaze being escorted through the corridor and later hears Everett scream as he is attacked in his room. Dr. Hellenbach pays her a visit and asks about her regrets. She lies, insisting she has none, and pleads to go home, but he tells her she is not ready. Sharyn is introduced to a group of other patients—Cassandra Franklin, Rizzo, Marjorie (whose eyelids are paralyzed), Lester (a criminally insane man), and Everett, a criminal attorney. Everett shares that his tongue was cut out but somehow grew back, while Cassandra explains that the facility is an experimental place and that she had been burned alive.

During the facility’s Indexing procedure, Rizzo is selected for treatment and reveals that he had been impaled. Sharyn watches as Hellenbach administers a healing serum to Rizzo, a moment that leads him to ominously remark, “he did this to himself.” As Sharyn wanders the halls, Hellenbach finds her and compels her to reveal personal details, including the story of her ex-boyfriend Nico, a drug trafficker who killed himself. A broken phone, a piano room, and a noose become part of the grim environment. Punishment soon follows: Sharyn’s left leg is amputated and then reattached, a procedure used to discipline noncompliance. Rizzo later visits Sharyn and speaks of the possibility that the military is harvesting subjects to build immortal soldiers. When Sharyn asks why his treatment was given, Hellenbach answers with menace, and she begins to understand that escape will be far from simple.

Everett hints at a tentative three-month release if they cooperate, but Sharyn reveals that she has seen Nico alive in the facility—a man she believes is dead for ten years. This fuels tension: Everett’s confidence falters, and Hellenbach reassures him that his file will be reviewed in three months, though Everett’s anger leads to the reappearance of his own punishment as his tongue is cut again.

Seeking a way out, Sharyn asks Cassandra about her experience, but Cassandra admits she does not know how long she has been there. The two schemers plot an escape, and Sharyn steals Hellenbach’s keys while pretending to stumble. They work through the doctor’s office and uncover a map of the compound, managing to move through the medication room without immediate capture. Nursing staff, however, close in, and Cassandra attempts to end her life by cutting her neck, creating a moment of diversion that helps Sharyn flee. An alliance grows between Sharyn and Rizzo after he protects her from an attack by Lester, but their fragile partnership falters when Rizzo makes an unwelcome move; in retaliation, Sharyn injures him and resumes the breakout.

Sharyn finally reaches the exterior and breaks into a run, the alarm blaring as staff chase her. She corners herself at a residential home outside, but a staff member tracks her down and brings her back to the facility. Back in the piano room, she awakens to find herself suspended and then dropped, dying in a grim display. Asked why the healing isn’t lethal, Hellenbach explains that killing is not how they operate here and questions her about her regrets once more, noting that she’s not a good liar.

Nico reappears and pulls Sharyn away from Hellenbach, insisting he won’t let her rot. The pair are confronted by Hellenbach as they move, but Nico overpowers him and the two escape again. They reach the edge of a cliff, with lava looming below, and a path across the lava begins to materialize as doctors toil to revive Sharyn on Earth. She crosses to the other side, but Nico cannot follow.

Sharyn wakes in a hospital bed to learn she had been placed in a medically induced coma and was clinically dead for about 15 seconds. She lifts her hospital gown to reveal a large bandage over her abdomen, and her husband and daughter come to her side. Back home, she searches for news and discovers an article in The New American Journal of Medicine about Dr. Hellenbach, confirming his death in 1969. She also finds references to Cassandra Franklin, who died after a mushroom poisoning. The final threads of the story show Sharyn placing flowers on Nico’s grave, suggesting a personal reckoning that lingers beyond the hospital walls.

Throughout this ordeal, the facility and its patients are presented as a morbid, interwoven world where healing and torment coexist, where the line between life and Hell is blurred, and where the possibility of redemption or damnation is decided by a perpetual cycle of suffering and, for some, a sliver of escape. The tale closes with Sharyn’s return to the ordinary world tempered by the unsettling memories and the eerie evidence that the hospital’s truth extends far beyond its doors.

Last Updated: November 22, 2025 at 16:00

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