While enjoying a day at the nail salon in the Bronx, Vivian learns from salon owner Becky about the looming sale of her business to Murnau Properties, a real estate company that is rapidly acquiring properties in the area. Shortly after her departure, Murnau broker Frank Polidori arrives to finalize the transaction, only to witness a horrifying event as a vampire attacks Becky.
Meanwhile, Miguel Martinez is busy organizing a block party aimed at fundraising to save Tony's bodega, which is facing closure due to gentrification. Accompanied by his close friends Bobby and Luis, who all have roots in the local corner store, Miguel raises concerns about the ongoing changes in their beloved neighborhood. In a tense moment, while putting up posters near a courthouse owned by Murnau Properties, Miguel is stalked by Slim, a member of the local gang known as Henny's crew. In a tragic turn, Slim meets his end at the hands of some mysterious men, forcing Miguel to seek refuge with Tony, hiding alongside Bobby and Luis from the lurking vampire.
Realizing the danger, the trio discovers that vampires don’t cast reflections after a close encounter. The following day, the friends decide to arm themselves with knowledge by watching "Blade" and brainstorming how to vanquish these supernatural beings. They take a bold step by visiting a Murnau Properties office in hopes of locating the vampires’ daytime hideouts. However, when confronted by Frank, he threatens the boys with the chilling reminder that being from the Bronx means they could very well disappear without a trace. Despite the threat, they manage to snatch a file from his desk and escape, only to discover a USB drive marked with plans for vampire nests scattered across the Bronx, along with a skeletal key.
With newfound determination, they uncover that the courthouse is the vampires' nest and stage a break-in. This leads to a nail-biting moment where Miguel inadvertently films himself awakening a vampire, setting off a frantic chase that ultimately results in their arrest for trespassing. When Miguel attempts to share his shocking evidence with skeptical Bronx residents, his footage of an empty coffin only garners laughter. Driven by desperation, he challenges Frank to step into sunlight, but is shocked when Frank complies and demands the return of the stolen file. It becomes clear that Frank is merely a pawn for the vampires, and the stakes rise when he hires Henny and his gang to hunt down the boys.
In a twist, Vivian makes her presence known at the bodega while in pursuit of Miguel. Unfortunately, in a horrific scene, Tony realizes her true nature as a vampire and pays the ultimate price for it. Miguel and his friends witness the transformation of their community as the bodega is boarded up, driving Miguel to take Tony's cherished Sammy Sosa bat and pledge revenge on the vampires for the tragedy they have caused.
A dangerous heist orchestrated by Henny and his crew results in their demise at the hands of the vampires. As they flee, they are escorted to Miguel’s home by Vivian, who they soon realize is the leader of the Murnau coven. They desperately plead with Miguel’s mother not to let Vivian in, knowing vampires can only enter with an invitation. Vivian, now exposed, demands the key back, which Miguel uses to defend his home—with holy water causing her to retreat.
The next morning, Miguel and his friends gear up to confront the coven at the courthouse. In a grand showdown, they manage to take down several vampires, but the key’s significance is highlighted when Vivian reveals it unlocks a box containing the ashes of the first vampire, capable of raising an undead army. Bobby cleverly manipulates Frank into realizing that he will never be accepted by the vampires, leading to his sacrifice but also giving the boys a fighting chance.
As the confrontation escalates, Vivian incapacitates Miguel, but the tide turns when the Bronx residents rally, brandishing homemade weapons. In a final act of courage, Miguel plunges Tony’s bat into Vivian, ending her reign of terror.
Two weeks later, as Miguel strolls past a mural honoring Tony on his way to the block party, he and his friends affirm their new identities as vampire hunters, determined to protect their community. In a vibrant show of unity, resident Gloria captures the moment on a live stream, sending a clear message to any future invaders—her community stands strong and united against all odds.
