Parker [Mark Wahlberg] and his partner Philly [Thomas Jane] pull off a high-stakes heist in a racetrack counting room, but an employee kills one of the thieves and wounds Philly, driving away with the stolen money and his family. Parker pursues the killer onto the track and shoots him dead, bribes the killer’s wife, and escapes with the score. The thieves are betrayed by their getaway driver Zen [Rosa Salazar], who shoots Philly and the others as a wounded Parker falls into a nearby river. Recuperating at a motel, Parker promises Philly’s widow Grace Webb to avenge her husband.
With help from fellow thief Grofield [Lakeith Stanfield], who runs a struggling theatre company, Parker tracks down Zen’s associate Reggie, who reveals Zen was a member of a death squad in her home country. Her fellow mercenaries kill Reggie and his driver, but Parker forces the surviving gunman to bring him to Zen. Killing her contact Bosco, Parker confronts Zen, who admits she used the racetrack score to fund a new score: Her country’s corrupt President De La Paz has hired a crime syndicate, the Outfit, to steal treasure from a shipwreck De La Paz will be displaying at the UN, in order to sell the $1 billion treasure himself.
Parker and Grofield meet with Zen and her comrades, led by Colonel Ortiz [Hemky Madera], who plan to seize the treasure on behalf of their fellow citizens. Parker, exiled from New York City by the Outfit’s leader Lozini [Tony Shalhoub], suggests they steal the treasure once the Outfit has stolen it from the UN. Parker and Zen question Bosco’s boyfriend, fighting off the Outfit’s men, and Parker drops Lozini’s lieutenant Kincaid [Nat Wolff] from a window while retrieving Bosco’s plans for the UN robbery, hidden inside a stuffed elephant.
Married thieves Ed and Brenda Mackey [Claire Lovering] and getaway driver Stan Devers [Chai Hansen] are recruited for the heist: The Outfit will transport the stolen treasure by automated garbage train, which Parker’s crew will derail. Zen attempts to seduce Parker, but her jealous comrade Mateo delivers him to the Outfit. Mateo is killed instead as Zen rescues Parker, and a phone call from Lozini reveals the Outfit is robbing the UN that night, forcing Parker’s crew into action.
Posing as MTA workers, Ed and Brenda subdue the Outfit’s inside man and hijack the train’s switchboard. A drunk Stan crashes the getaway truck and nearly runs over Grofield, who shoots the failsafe brake, derailing the train. Parker, Zen, and Grofield discover the containers of treasure have been replaced with rocks, and Stan is shot in the leg as they flee in a stolen police car.
The crew turn on Parker for being outsmarted by the Outfit, but he convinces them to go after the shipwreck’s figurehead worth $500 million. Grofield poses as a suicidal jumper as he and Parker lure Kincaid’s bodyguard to the roof, throwing him to his death, and question the injured Kincaid, whose girlfriend reveals the figurehead is being sold to billionaire Phineas Paul [Chukwudi Iwuji]. Parker kidnaps Phineas, shooting Mark Cuban in the process, and learns the figurehead is inside a secure facility in Green Brook Township, New Jersey.
Phineas escapes from an inebriated Stan and warns Lozini, who arrives at the facility just as Parker’s crew drive off with the figurehead. The thieves escape in a snowy chase but lose the figurehead, which Phineas discovers is a replica. He informs De La Paz, who assumes Lozini has double-crossed him. Lozini and his men return to the facility, where Parker waited until the time-lock on the real vault opened. Destroying the genuine figurehead with explosives rather than let it fall into the wrong hands, Parker kills Lozini and escapes as De La Paz’s guards slaughter the Outfit.
Leaving the crew with valuable jewels he saved from the figurehead, Parker confronts Zen, who suggests he join her for a simpler life in her home country, but Parker kills her to avenge Philly and the others. As Phineas and De La Paz’s crimes are made public and Ortiz is named the new president, Parker delivers a share of the jewels to Grace Webb, and he and Grofield return to their lives of crime.
