An American musician and conservative conspiracy theorist, Annie Annie Hardy livestreams while driving, turning comments from the live chat into improvised lyrics. Frustrated by the COVID-19 pandemic restrictions and homelessness in Los Angeles, she flies to London to surprise her friend and former bandmate Stretch, who now works as a food delivery driver. Stretch’s girlfriend, Gemma Gemma Moore, immediately clashes with Annie over politics and social issues.
Annie accompanies Stretch on a delivery run, and her anti-mask views spark tension with restaurant owners. When she refuses to remove her MAGA hat after they return home, Gemma attacks her. That night, after overhearing Gemma urging Stretch to kick her out, Annie steals Stretch’s car and phone and takes a delivery job meant for him. She arrives at a closed restaurant, where the owner offers money to transport an elderly woman named Angela Angela Enahoro to a destination she has scribbled down.
Angela soils herself, forcing Annie to stop at a diner, where she’s startled to discover a tattoo of Ariana Grande on Angela’s stomach. A woman enters to search for Angela and attacks Annie, who flees the diner with Angela. Stretch tracks Annie down via her livestream and forces his way into the car. The two argue and pull over, and Angela vanishes. Stretch finds her standing on top of a tree in a nearby forest, but falls while trying to reach her, followed by Angela slowly floating to the ground. The diner’s woman returns with a shotgun, attempting to kill Annie and Stretch, who escape in the car with Angela. They peel away Angela’s face mask and discover that her mouth is stapled shut.
Annie and Stretch try to flag down a passing car, which runs over Stretch. The driver reveals herself as the diner-woman and claims to be Angela’s mother, showing Annie a photo of a young Angela with the same tattoo on her stomach to prove her claim that Angela is only 16. Annie tries to drive away in the woman’s car but crashes it and is attacked again. Stretch recovers, helps Annie trap the woman’s arm in the steering wheel, and accidentally snaps it. Angela reappears, rips her mother’s head off, and pursues Annie and Stretch as they flee.
The chase leads them into an abandoned amusement park, where Angela finds and kills Stretch. Annie escapes in a car, but Angela causes another crash. Angela pushes the car into a lake with telekinetic power, yet Annie manages to trap her in the car and swims to shore as the vehicle sinks. Unaware, Angela quietly rises from the lake and follows behind in the sky.
Annie discovers a remote house that matches the destination she was asked to escort Angela to. Inside, she encounters occult symbols and cult members who slash their own throats and die before her. Angela attacks again, and Annie kills her with a cult member’s knife. A large, slug-like humanoid creature emerges from Angela’s mouth and chases Annie, who finds Stretch’s car and retrieves his keyboard from the back seat, then uses it as a weapon to strike the creature dead. Exhausted, she collapses into Stretch’s car and resumes her livestream, improvising a rap about the bizarre ordeal she just survived. The credits of fear, faith, and survival roll as she drives away.
