Retired thief Roy Egan, Harvey Keitel, comes out of retirement to help his youngest brother, Lee Egan, Timothy Hutton, with a jewelry heist in Palm Springs. Along for the ride are hired muscle Jorge Montana, [Wade Dominguez], and wheelman Skip Kovich, [Stephen Dorff]. The job goes down the next day, and, thanks to Jorge's scrambling of the police monitors and traffic signals, their getaway is clean and fast, leaving little room for error.
In Skip's motel room, his girlfriend, Gena, [Dana Barron], voices how little money he will be receiving from the heist. At the trailer park, Lee and Jorge share beers and talk about how much each will make, when Skip suddenly shoots them. Roy, who was in the bathroom, hears the gunshots, slams the door on Skip, and runs for it. He steals a car and heads to Los Angeles, where he rents a room and starts plotting. On the way, he stops at Lee's house to inform his wife Sunny, [Tamara Clatterbuck], about her husband's death and to ask if she knows Skip's whereabouts.
Skip employs Odell Williams, [Michael Jai White], as protection against Roy, and proceeds to deal with his debt to loan shark Harvey, [Elliott Gould], who is connected with the Chinese mob. Skip convinces Harvey to use his connections to track down Roy, in exchange for more money on top of what he already owes him.
Roy goes to Jorge's home and asks his widow, Rachel Montana, [Famke Janssen], if she knows Skip. He informs her that Skip killed Jorge, and Rachel angrily dismisses him. Back at his motel, Roy is found by two members of the Chinese mob and kidnapped, but he frees himself, killing his captors in the process.
The next morning, Rachel finds a bruised and bloody Roy lying in her yard. She cleans him up and Roy offers her $5,000 to take care of him. Once he recovers, Rachel asks for $100,000 instead. Roy refuses at first, but when she gives him Jorge's address book full of contacts – including Skip – he accepts. Rachel also tells Roy where the Chinese mob launders cash and gives him a Saint Christopher medal for protection.
Roy attacks Uncle Luke, [François Chau], the man in charge, and takes Skip's money, but unknowingly leaves his motel key behind. Uncle Luke tells Skip about the key Roy left behind. Chinese mobsters later attempt to kill Roy in his motel room, but Roy is waiting for them.
Skip kidnaps Rachel. He goes to a trailer where his girlfriend Gena discovers that Odell has sent two of his guys to get the money Skip owes them. They take Gena hostage and Skip kills them both, purposefully killing Gena in the process.
Skip and Roy plan to meet at a refinery, and when Roy arrives, he enters a gun fight with the mobsters after Skip. Roy overpowers and kills them, though he is severely wounded, yet still manages to beat Skip to death with his bare hands. He rescues Rachel, who speeds a barely conscious Roy to a hospital. When she returns, both Roy and her car are gone, but he has left her money in a duffel bag.
Rachel and her children bury Jorge and relocate to Port Arthur, Texas. One day, the postman delivers a small package to her. She opens it and finds the religious medal she gave Roy, a quiet sign that he may still be alive.
