Rudy Carges [Conor Donovan] and his overweight friend Leonard Fisher [Jesse Camacho] spend the night hiding in their treehouse after two teenage bullies, Jeff [Martin Campetta] and Kenny [Michael C. Fuchs], threaten to destroy it. When the bullies return, they set the treehouse ablaze, unaware that the youths are inside; Leonard escapes unharmed but collapses on the ground, while Rudy dies offscreen. Rudy's twin brother, Jacob, a boy marked by a large birthmark, decides to seek revenge against those bullies.
At the hospital, Leonard learns he has lost his sense of taste and smell. A gym teacher pressures him to go on a diet, which clashes with his obese family’s resistance to change. Meanwhile, Malee [Zoe Weizenbaum], a friend of theirs, begins to form a connection with Gus Maitland [Jeremy Renner], a grief-stricken patient under the care of her mother Carla Chuang [Annabella Sciorra]. As Malee’s admiration grows, she begins to see Gus as her “soul mate” and even tweaks her recital song to suit his tastes. She eventually slips into Gus’s house at night to observe him grieving, and in a desperate move, steals his gun and hands it to Jacob the next day.
Jacob’s family begins to fracture after Rudy’s death. His mother grows furious when Jeff and Kenny receive only a short juvenile sentence, while his father views Rudy’s death as an accident. Jacob spends months visiting Jeff and Kenny, threatening them until Jeff commits suicide. After this, Jacob forgives Kenny, who is released earlier and heads toward New Mexico. In a parallel arc, Leonard’s father decides to take Leonard’s sisters to Florida, while Leonard himself pushes his family toward healthier eating. A dramatic gas leak in their home leaves them hospitalized.
As the story moves toward its climax, Jacob and Kenny form a dangerous alliance and plan an escape to New Mexico. Malee continues to visit Gus and, at one point, revisits painful memories with him. Later, Jacob confronts the consequences of violence when he and Kenny reunite near a construction site and Jacob insists on going with him to New Mexico. He grabs Gus’s gun and, in a tense moment, tells Kenny, > you killed him, before firing. He buries Kenny at a makeshift grave and returns to the daytime world, where he sees Gus spreading cement above Kenny’s grave to erase the evidence.
Back home, Malee’s presence persists as she visits her estranged father, and Leonard’s family slowly starts to eat healthier. Jacob returns home without explicitly narrating his actions, leaving the truth of what happened to linger beneath the surface as the film circles back to its emotional core: the consequences of grief, anger, and the difficult path toward closure.