In Buffalo, we follow the life of Henry, a seemingly aimless toll collector navigating the lonely highways of New York. Working tirelessly yet without any ambitions or dreams, he meanders through life in a haze, much to the discontent of his wife, Debbie. Their relationship teeters on the edge as she yearns for a more fulfilling existence.
The monotony of Henry's life is abruptly disrupted when his friend Eddie drops by one fateful morning with an invitation to join a baseball game. While driving to the game in Henry's car, Eddie requests a quick stop at an ATM. However, in a shocking turn of events, Eddie, along with two accomplices, seizes the opportunity to rob the Buffalo Savings Bank, ensnaring Henry in their web of crime. Consequently, Henry finds himself arrested as an unwitting accomplice, despite his innocence.
Faced with the dilemma of sacrificing his friends, Henry opts for silence and takes full blame, landing him behind bars. There, he crosses paths with Max, a charismatic conman who thrives in the comforts of prison life. With Max's irrepressible spirit, he plants a seed in Henry's mind: to discover one's true purpose, one must first dare to dream. Meanwhile, Henry's world crumbles as Debbie chooses to divorce him and tie the knot with Joe, one of the robbery’s perpetrators.
After serving 18 long months, Henry emerges with a renewed sense of purpose. Drawing from his time in prison, he decides that if he has paid for a crime, why not indulge in the thrill of committing one? During his newfound exploration, he discovers an old bootlegger’s tunnel that leads directly from the bank to a theater across the street. With this devious plan shaping up, he persuades the reluctant Max to petition for his long-overdue parole—an essential move to pull off their ambitious bank heist.
Embracing a dual life, Henry auditions for a role in Anton Chekhov's classic play The Cherry Orchard in the theater, while Max eagerly “volunteers” to lend a hand backstage. As rehearsals unfold, Henry finds himself captivated by the enchanting leading lady, Julie, igniting feelings he thought were long lost.
During the meticulously planned heist, Debbie's husband Joe is roped into the scheme to help clear out the tunnel’s mud. As the day approaches, he alerts Eddie about the operation, culminating in a volatile mix of ambition and betrayal. When the robbery kicks off, Eddie attempts to hoard all the funds for himself but is soon overpowered by Max, leaving Eddie trapped in the vault.
In the exhilarating climax, as the trio makes their escape, Henry orders Joe to halt the car. The thrill of the heist exhilarates him as he bids farewell to Max, choosing to cherish his newfound connection with Julie instead. Ultimately, Buffalo illustrates that through hardship and chaos, one can discover their purpose, dream bravely, and make choices that resonate with their true identity.