Gana returns to his hometown of Visakhapatnam, India, eager to participate in his sister Priya's joyous wedding celebrations. However, after her engagement, he is devastated to discover her in a moment of despair, attempting to take her own life. In a heart-wrenching confession, Priya reveals that she is pregnant but is uncertain about the identity of the father. Gana consents to inform her fiancé, Ravi, who, showing maturity and understanding, supports Priya through an abortion while promising to keep this sensitive matter under wraps. Under Gana's encouragement, Priya finds the strength to move on and eventually marries Ravi, leaving her troubled past behind.
After the wedding, Gana takes matters into his own hands, confronting and violently interrogating men who had previously harassed Priya, but to his dismay, learns that they were not responsible for her pregnancy. The situation takes a darker turn when another woman, Sadhana, who shares a similar fate of mysterious impregnation, ends her life. In her poignant suicide note, Sadhana describes her disbelief at becoming pregnant without any knowledge of how it happened. When Gana engages with her grieving parents, he uncovers hospital records indicating that Sadhana had been admitted after fainting three months prior—an incident mirrored by Priya's own hospital admission.
Determined to unravel this disturbing mystery, Gana discovers a troubling pattern: several women, including Sadhana, Priya, and others named Lakshmi and Monica, had been similarly treated at the hospital under baffling circumstances. The plot thickens when Gana's girlfriend, Neha, alerts him to her friend, who recently fainted at the mall and was taken by an ambulance that seems to have gone missing. Without delay, Gana embarks on a frantic mission to track down the ambulances and find Neha's friend. Despite the challenges ahead, he employs his parkour skills to chase down an elusive ambulance, ultimately rescuing Neha's friend from peril.
As the narrative unfolds, the ominous figure of Dr. Manoj Kumar emerges as the mastermind behind these sinister occurrences. This pathologist exploits his position to abduct attractive women, sedating them before subjecting them to heinous acts. He cleverly erases evidence of his crimes, believing that his profession shields him from suspicion. After Gana disrupts his operations, Manoj takes extreme measures to eliminate anyone connected to his crimes, including the fishermen who assisted him.
Tension escalates as Gana reveals the emotional turmoil of his family to Neha, and soon, the horrifying truth strikes with the abduction of a minister's daughter named Sowmya. When she regains consciousness during her assault, the situation culminates in a brutal climax as Manoj kills her to prevent exposure, leaving her body as a chilling message outside the police station. Gana, relentless in his pursuit of justice, utilizes Neha's assistance to infiltrate Sowmya's electronic records, gaining access to pivotal evidence.
In a gripping turn of events, Gana uncovers the shocking involvement of Hypomacene, a contraband drug that induces hypoglycemia—explaining the sinister connection among the victims. Armed with new information, Gana confronts Manoj under the pretense of needing his help, but as the plot thickens, Manoj's inherent sadism comes to light, revealing his pathological tendencies rooted in a troubled childhood.
The situation ultimately leads to a frenetic car chase, and Gana finds himself at Manoj's home, where he stumbles upon horrifying evidence of the doctor's gruesome acts. As Manoj's distorted psyche unfurls, Gana faces him in a final confrontation. The struggle culminates in a harrowing showdown, where Gana secures ultimate vengeance by dropping a chandelier on Manoj during a climactic moment, extinguishing his twisted existence.
As the dust settles, Gana receives an unexpected call from his father, sending him into a panic about Priya’s safety. Rushing home, he is met with an unforeseen twist—Priya is now expecting a child with Ravi, signaling a bittersweet resolution to the tumultuous events that have transpired.