Year: 2020
Runtime: 87 min
Language: English
During a grueling double shift, Nurse Mandy’s struggles with addiction intertwine with a dangerous situation involving organ trafficking. When her cousin makes a critical error during a kidney delivery at an Arkansas hospital, a chaotic sequence of events unfolds. Mandy finds herself scrambling to rectify the mistake and secure a replacement organ, confronting escalating threats and difficult moral choices in a desperate attempt to maintain control.
Warning: spoilers below!
Haven’t seen 12 Hour Shift yet? This summary contains major spoilers. Bookmark the page, watch the movie, and come back for the full breakdown. If you're ready, scroll on and relive the story!
Read the complete plot breakdown of 12 Hour Shift (2020), including all key story events, major twists, and the ending explained in detail. Discover what really happened—and what it all means.
In 1999 Arkansas, we meet Mandy, an overworked nurse battling a severe drug addiction. Her desperate measures to finance her habit extend beyond stealing patient medications—she is involved in a sinister scheme of harvesting patient organs for profit. Partnered with desk nurse Karen and recently enlisting her cousin Regina for added help, Mandy delivers harvested organs to trafficker Nicholas.
The chaotic night begins when Mandy hands over a harvested kidney inside a cooler to Regina at the hospital’s rear. However, in a moment of confusion, Regina mistakenly takes a cooler filled with soda instead. The wrathful Nicholas demands to have the kidney, or else he will claim Regina’s. In a frantic search for the organ at the hospital, Regina turns to a shocking choice. When Mandy refuses to assist her, Regina, disguising herself as a nurse, commits murder by poisoning a patient with bleach in a desperate attempt to procure a kidney. To her dismay, Mandy explains that the victim was on dialysis, leaving him with unusable kidneys.
The arrival of the police complicates matters as they start to investigate the murder. In a spiral of violence, Regina escalates her actions, threatening to reveal the organ trafficking operation unless Mandy helps her. Reluctantly, Mandy agrees, instructing Regina to remain outside. As panic sets in, Regina encounters one of Nicholas’s henchmen and, in a misguided attempt, kills a random skateboarder, hoping to procure his kidney but mistakenly removes his bladder instead.
Inside the hospital, Mandy takes matters into her own hands, overdosing a patient to harvest his kidney surreptitiously. She leaves the organ in a cooler near a vending machine, only to discover it has vanished by the time Regina arrives.
Meanwhile, Nicholas’s intimidating henchman Mikey stirs chaos within the hospital, posing a threat to Regina. In a bold move, Regina proposes to kidnap a comatose patient to satisfy Nicholas, unaware that this patient is actually Mandy’s abusive half-brother, who is also struggling with addiction. Mandy intervenes, and the two join forces to subdue Mikey. The police erroneously conclude that Mikey is the perpetrator behind the hospital murders.
As Regina exits the tumultuous scene, hospital guest Mr. Kent reveals he’s been stumbling upon coolers filled with kidneys throughout the night. Exhausted, Mandy opts to take a nap in her truck. The film culminates with her returning to the hospital to begin yet another grueling shift, not long before Nicholas reappears, hinting at the unending cycle of horror and addiction that defines their lives.
Last Updated: November 03, 2024 at 13:05
Don't stop at just watching — explore 12 Hour Shift in full detail. From the complete plot summary and scene-by-scene timeline to character breakdowns, thematic analysis, and a deep dive into the ending — every page helps you truly understand what 12 Hour Shift is all about. Plus, discover what's next after the movie.
Track the full timeline of 12 Hour Shift with every major event arranged chronologically. Perfect for decoding non-linear storytelling, flashbacks, or parallel narratives with a clear scene-by-scene breakdown.
Discover movies like 12 Hour Shift that share similar genres, themes, and storytelling elements. Whether you’re drawn to the atmosphere, character arcs, or plot structure, these curated recommendations will help you explore more films you’ll love.
12 Hour Shift (2020) Scene-by-Scene Movie Timeline
12 Hour Shift (2020) Movie Characters, Themes & Settings
Movies Like 12 Hour Shift – Similar Titles You’ll Enjoy
Night Shift (1982) Complete Plot Breakdown
Night Shift (2024) Full Movie Breakdown
Shadow Hours (2000) Full Summary & Key Details
Blackout (2024) Full Movie Breakdown
Pusher (2012) (2012) Spoiler-Packed Plot Recap
13 Sins (2014) Story Summary & Characters
Bringing Out the Dead (1999) Story Summary & Characters
Countdown (2019) Full Movie Breakdown
Mandy (2018) Detailed Story Recap
Trouble Every Day (2001) Complete Plot Breakdown
Twelve (2010) Complete Plot Breakdown
Blackout (2022) Ending Explained & Film Insights
The Good Nurse (2022) Full Movie Breakdown
12 Rounds (2009) Complete Plot Breakdown
American Mary (2013) Complete Plot Breakdown