In 2007 Cleveland, fourteen-year-old Edie Meaney, Samara Weaving, is pulled over by police while driving her drunk parents home from buying drugs at a bar. To save them from prison, Edie’s father urges her to speed away, but she crashes the car. Her mother is killed and her father is left a paraplegic, while Edie survives a series of abusive foster homes until she is rescued by John, Karl Glusman, a young petty criminal. Falling in love, Edie and John carry out numerous robberies for mob boss Nico, Andy Garcia, who nicknames her “Eenie Meanie.”
Fourteen years later, Edie has left her life as a getaway driver behind, and finally broken up with John. Working at a bank to put herself through community college, she is knocked unconscious during a robbery; taken to the hospital, she learns she is pregnant. Against her better judgment, Edie visits John, who is being interrogated by Nico’s goons, and reluctantly uses her driving skills to save him.
John reveals he has kidnapped Leo, a card counter in Nico’s employ, who refused to help him with a scheme behind Nico’s back. Edie demands that they make amends, but Leo is accidentally killed by a passing truck. Furious to be pulled back into John’s reckless decisions, Edie meets with Nico and his right-hand man George, who hold John accountable for the loss of Leo’s earnings. In exchange for sparing John’s life, Nico forces Edie to accept a job: stealing a car containing $3 million in cash, the prize for an upcoming poker tournament at a casino in Toledo.
The heist’s planning is overseen at Gary’s bar by the Chaperone, who considers John a liability, but Edie remains loyal to her ex-boyfriend. With inside help from casino staff and a series of payoffs, the prize Dodge Charger is replaced with an identical model outfitted for the robbery. At the casino, Edie and John run into rival getaway driver Perm Walters, but Nico assures them he is not involved. Suspicious, Edie and John reach out to her father for help, but he has made a reformed life for himself and his new family. Edie tells John she is pregnant, and they spend a romantic night together.
The tournament concludes as the prize money is loaded into the car, and Edie manages to drive the bulletproof Charger off the casino floor. Leading police on a high-speed chase, she is intercepted by Perm. John flips his own car in pursuit and Edie stops to pull him from the wreck, as Perm takes off in the Charger. Failing to find a hidden tracker, Perm is killed in a shootout with John. Edie delivers the cash to Gary and the Chaperone as planned, but John kills them in a desperate plan for him and Edie to take the money for themselves. Realizing his mistake, John promises to change his reckless ways, but Edie shoots him dead.
She brings the money to Nico, who has overlooked George skimming from him for years, but he is heartbroken to realize that George hired Perm. Sharing her childhood dream of a home with more than one bathroom, Edie leaves with a share of the money as Nico disposes of George. Sometime later, Edie has started her own auto repair business and a new life with her son.