DogMan

A former Officer Knight whose head is transplanted onto a canine body after a bomb incident. He inherits Knight's duties, grapples with loneliness after Knight's death, and becomes a beloved figure who protects the city while forming a bond with Li'l Petey.

An evil orange cat mastermind who plots destruction and clones himself to create Li'l Petey. He wrestles with his violent past, eventually teams up with Dog Man to stop greater threats, and pursues redemption, sharing custody of his son after being pardoned near the end.

A newborn clone of Petey who initially shows no interest in evil. Adopted by Dog Man, Li'l Petey forms a delicate bond with his adoptive father and helps drive the redemption arc by challenging Petey's choices.

An evil telekinetic fish resurrected by Petey and reprogrammed to destroy good. He ultimately seeks redemption after Petey reforms, aiding Dog Man in overcoming the threat and accepting a new path.

Petey's father whose harsh, dismissive attitude underscores Petey's troubled upbringing. His appearance adds emotional friction and highlights the cycle Petey strives to break.

The original officer whose head ends up on Dog Man's body after the bomb. His death becomes the catalyst for Dog Man's transformation and the city's trust in a cybernetic canine cop.

A city reporter following the Dog Man and Li'l Petey saga, she helps chronicle the chase for Li'l Petey and the evolving turmoil in Ohkay City.

Dog Man's former girlfriend who leaves after selling their house, highlighting the personal costs and loneliness surrounding Dog Man's new life.