It is the fall of 2000. Alice is a sexually inexperienced but curious junior at a strict Midwestern co-ed Catholic high school, where Father Murphy instructs her Morality class that any sexual activity not aimed toward procreation within a heterosexual marriage is a sin, with eternal damnation as punishment. She struggles with accepting her burgeoning feelings of sexual desire after both Father Murphy and her best friend, Laura, cause her to feel ashamed of them.
The following Monday, the school is abuzz with a rumor that Alice “tossed the salad” of a classmate, Wade, at Laura's party over the weekend. Alice denies this, admitting to not knowing what the phrase means. The rumor reaches Mrs. Veda, who prevents Alice from serving at Mass. Later that day, during the sacrament of reconciliation, Alice confesses venial sins to Father Murphy and receives a light penance of twenty prayers, which she immediately and fervently fulfills in the school chapel, Father Murphy and Mrs. Veda's words about sex echoing in her mind.
Alice and Laura both decide to attend the school's next Kirkos spiritual retreat— Alice to return to the path of righteousness, and Laura to be accepted by Nina, a popular senior. When they arrive on the retreat campgrounds, Laura is excited to find that Nina is a retreat leader, while Alice eyes Chris, a hunky senior who is also a retreat leader. Chris is friendly and enthusiastic, and after Alice is assigned to his group, the two begin to bond. That night, while playing on her contraband cell phone, Alice accidentally discovers that she can pleasure herself using her phone's vibrating feature; however, she stops soon after looking at the crucifix hanging in her room.
On the second day of the retreat, Alice fakes an injury on a hike to get closer to Chris. Nina confiscates Alice's phone; and, as a punishment, Father Murphy assigns Alice to cleaning duties around the retreat house. Once she is alone, she logs onto an AOL chat room from Father Murphy's office computer to ask what “tossing salad” means; before she can find out, the sound of footsteps causes her to hastily shut off the computer and leave. She runs into Nina, who lightheartedly guilts Alice about Alice's presumed sexual encounter with Wade, another instance of Alice's inability to be free of the rumor even while “on Jesus's time.”
On the third day of the retreat, Father Murphy announces his discovery of an explicit chat on his computer; of course, no one claims responsibility. He later pushes Alice to confess to acting on her sexual temptations with Wade and doesn't believe her insistence that nothing happened. Alice confronts Wade about his complicity in the rumors leading to the incident, and he leaves without admitting his fault or apologizing. Again, on cleaning duty, Alice witnesses Nina kissing, then fellating, another senior leader in the woods; Alice shares this with Laura, who refuses to believe Alice, accuses Alice of breaking into Father Murphy's office, and ends their friendship, calling Alice a “pervy psycho.” Alice returns to Father Murphy's office and frames Wade for the earlier break-in; while hiding to make her escape, she catches Father Murphy masturbating to a pornographic video saved on his computer. Outside, finding herself alone with Chris, Alice kisses him, but he becomes overwhelmed and runs away. That night, Alice flees the campgrounds and stumbles upon a lesbian bar, where she and the owner, Gina, commiserate about how the fear of damnation can warp an adolescent's development. Gina counsels Alice and gives her a ride back to the retreat, encouraging Alice to look into colleges on the West and East Coasts and finally assuaging Alice's curiosity about what “tossing salad” means.
On the last day of the retreat, Alice befriends a socially awkward classmate while Father Murphy pulls Wade aside. With Wade on the hook for the explicit chat incident, Laura makes peace with Alice. At a whole group sharing session, Alice reminds the retreat attendees that everyone is “hiding stuff” and implores them to treat each other with honesty and respect, as Jesus wanted.
Back at school, Alice reassures a still-uncomfortable Chris that they can just be friends. Returning to reconciliation with Father Murphy, Alice boldly reveals that while on the retreat she saw a video of people having sex—both of them knowing, but not discussing, the implications of her confession. Father Murphy assigns a heavier penance of one hundred prayers, but instead of remaining in the chapel, Alice goes home to rewatch and masturbate to the sex scene in Titanic.
