Twisted (2026) Plot Summary & Ending Explained

The ending of Twisted delivers a darkly poetic resolution to the intertwined stories of a grieving neurosurgeon and the con artist who becomes his unwilling subject. After Dr. Kezian successfully transplants Paloma's brain into the body of his deceased wife, Rebecca, it initially appears that his obsessive quest to cheat death has succeeded. The film's final scenes show the doctor and the resurrected Rebecca on a seemingly blissful vacation, suggesting that Kezian has gotten away with his horrific experiments. However, this victory is short-lived. The woman Kezian has brought back is not purely his wife—she retains a crucial part of Paloma's consciousness, and with it, a burning need for retribution.

In a fitting turn of justice, Rebecca turns on Kezian and slices his throat, ending his life just as he ended so many others. This moment cements the film's thematic core: both Kezian and Paloma were ultimately driven by an all-consuming love for their partners, but the doctor's grief curdled into a god complex that justified any atrocity. Paloma, by contrast, was never a killer; she was a con artist who stole from the wealthy but never intended genuine harm. The tragedy is that Smith, Paloma's partner who died trying to save her, became collateral damage in Kezian's madness. In the end, Twisted suggests that while love can be a powerful motivator, the refusal to accept loss—when taken to Kezian's extreme—destroys everything it touches.