Two teenage girls, Nicky Marotta Robin Johnson and Pamela Pearl Trini Alvarado, meet in the New York Neurological Hospital, each there for a mental health evaluation. Pamela is deeply depressed and insecure, feeling neglected and exploited by her father, David Pearl Peter Coffield, a wealthy commissioner campaigning to “clean up” Times Square. Nicky, by contrast, is blunt and street-smart, with dreams of making music, and she’s in the hospital after a brush with the police. The two women share a room, and a fast friendship grows: Nicky admires Pamela’s lyrical spirit, while Pamela appreciates Nicky’s unflinching honesty and resents the way doctors talk down to her.
When Pamela is released, she returns to the hospital ostensibly for a social-work appointment with Rosie Washington Anna Maria Horsford, but her real plan is to break Pamela out. The two escape together, stealing an ambulance, and vanish into the shadowy alleys before hiding out in an abandoned warehouse on the Chelsea Piers. From that shelter, they forge a pact to call for help by shouting each other’s names whenever trouble arises, turning their dire situation into a shared vow of loyalty and rebellion.
A city-wide manhunt unfolds as David Pearl denies responsibility and accuses Nicky of kidnapping his daughter, insisting Pamela needs medical attention. In the midst of the pursuit, a local radio voice comes into play: Johnny LaGuardia Tim Curry, a veteran DJ broadcasting from a penthouse studio above Times Square. He grows convinced that Pamela’s disappearance mirrors the distress he’s picked up in the public’s mood, and he uses his platform, WJAD, to reach out to the girls. This unlikely alliance helps them reframe their struggle as a message to a larger audience and gives them a chance to channel their feelings into music.
With LaGuardia’s support, the two girls begin writing songs and form an underground punk duo, the Sleez Sisters. LaGuardia sees their raw energy as a counterpoint to David Pearl’s glossy, sanitizing campaign to gentrify Times Square, and he helps them broadcast their voice beyond the hospital walls. When an open letter to Pamela appears in a newspaper, printed with the help of Rosie, the girls perform a bold, live set on WJAD that marks their rise to notoriety and street-level fame. Their rebellious mood intensifies as they start to gain attention by staging anarchic acts, such as tossing televisions from rooftops, a symbolism of rejecting control and consumer culture.
As the duo’s bond deepens, tensions emerge. Pamela begins to settle into a sense of herself and questions the path laid out for her, including her relationship with LaGuardia. Nicky, feeling a pull toward the wild frontiers of the Sleez Sisters’ future, grows jealous of Pamela’s budding autonomy and of any closeness she feels with LaGuardia. A heated break happens after a late-night confrontation in their warehouse hideout—the two friends throw LaGuardia and Pamela out, and Nicky unravels, destroying the journal she shared with Pamela. After a failed attempt to drown herself, Nicky searches WJAD for a response, demanding a slot on the air, though LaGuardia never obliges. In a crucial moment, Nicky’s voice breaks through as she calls out Pamela’s name, a plea for help that reframes their rift as a shared crisis demanding bonding rather than blame.
LaGuardia ultimately takes Pamela to Nicky, and Pamela decides to end the dangerous tug-of-war with LaGuardia. She accompanies Nicky to the center of Times Square, where David Pearl’s influence looms large. Pamela orchestrates a midnight, impromptu concert on the rooftop of a grindhouse at 42nd Street, alerting fans across the city to descend on Times Square. The plan uncovers a communal hunger for art outside official channels, and the message is clear: a city can be moved by two young women who refuse to be defined by fear.
Nicky steps into a garb of garbage bags and bandit-like makeup, performing atop the marquee roof as a cheering crowd surges below. As police close in from behind, she dives into the awaiting blanket held by fans, vanishing into the throng and the night. Pamela watches, a mix of pride and sorrow washing over her, as her friend disappears into the city’s electric darkness, leaving the future uncertain but the moment unforgettable.
