Coyote Bus Lines unveils Cyclops, a state-of-the-art articulated jumbo bus designed to offer non-stop service between New York City and Denver. Soon after the engine is equipped with nuclear fuel, a bomb injures Professor Baxter, the scientist in charge, Harold Gould. Cyclops itself remains undamaged, but the company loses both its driver and co-driver.
Camille Levy, the Cyclops designer and the professor’s daughter, must turn to her old flame Dan Torrance, Joseph Bologna, a once-promising driver who was tainted by a Mount Diablo crash and rumors of cannibalism. Torrance blames his co-driver for the alleged cannibalism, insisting he survived by eating the seats and luggage and even parts of a passenger’s foot that were included in a stew. Narrowly surviving an assault by vindictive fellow drivers with the help of John Beck as Shoulders O'Brien, Torrance is recruited to drive Cyclops. The film threads a tense thread of redemption through his backstory as he straps into the helm of the ambitious project.
Meanwhile, a sinister tycoon known as Ironman, encased in a huge iron lung, plots to destroy Cyclops. He directs his brother Alex to sabotage the bus using time bombs. Alex would prefer a far more dramatic earthquake plan, but Ironman insists that the bus be destroyed and discredited. Before the maiden voyage, Alex sneaks aboard and hides a bomb within Cyclops. Alex’s scheme is driven by a ruthless belief that outrage and fear will cement Ironman’s control over the business.
Amid public fanfare, Cyclops leaves New York for Denver. Among the passengers are the Cranes—a neurotic married couple awaiting their divorce; Claude Crane, Richard Mulligan as Claude Crane, and Sybil Crane, Sally Kellerman as Sybil Crane; Father Kudos, René Auberjonois who has lost his way; Dr. Kurtz, Bob Dishy a disgraced veterinarian; Emery Bush, Richard B. Shull a man with only months to live; and Camille Levy, Lynn Redgrave whose father died in the Mount Diablo crash. The list of travelers also includes a colorful mix of other minor passengers who populate the long corridor of the Cyclops, giving the journey a human texture beyond the technical marvel of the vehicle.
At first, Cyclops advances with confidence, and Torrance pushes the bus past a wind barrier that techs describe as breaking wind, reaching speeds that turn the trip into a showcase of power and precision. Yet the mission’s tension deepens when Dan discovers the hidden bomb and disarms it just seconds before an explosion rips through another part of the bus. The moment marks a turning point: Cyclops roars onward, but now Dan must confront both the mechanical challenge of keeping the craft intact and the moral weight of delivering a non-stop service to a destination that grows more perilous with every mile.
The journey grows perilous as a truck smashes into the upper deck windshield, and the bus careens toward the edge of a cliff. In a desperate bid to keep the vehicle from tipping, Dan and Shoulders shift weight by jettisoning all passenger luggage and then pumping the bus’s entire carbonated beverage supply into the galley at the far end, a calculated move to tilt the mass balance back toward safety. The plan buys precious seconds, but it also underscores the extremity of the situation and the ingenuity the crew must summon to survive.
Ironman’s sabotage plot shifts into a new gear when Alex—Stuart Margolin—persuades Ironman to unleash the earthquake scheme. Ironman’s plan is thwarted when Alex secretly sets the coordinates for Ironman’s own house instead, turning the weapon back on the would-be aggressor and adding an eerie twist to the battle of wits aboard Cyclops. The tension hangs on every mile as the bus presses toward its long-awaited Denver terminal, even as the crew confronts lingering threats from those who would rather see the project fail than succeed.
Just twenty-five miles outside Denver, disaster clips the edge of possibility: the Cyclops finally buckles under the strain as the front and rear halves split apart. The dream of a non-stop link between two major cities collapses in a dramatic, harrowing moment that tests every survivor’s resolve and redefines what realism looks like on a road that dares to push beyond the limits of conventional transit. The film closes on a note that blends triumph with tragedy, leaving the fate of Cyclops and its passengers open to interpretation while preserving the memory of a journey that began in bold invention and ended in an extraordinary test of human courage.