Funny People

George Simmons, a successful comedian, receives a devastating diagnosis of acute Myeloid leukemia. Faced with the reality of his own mortality, he grapples with profound loneliness amidst his fame.

George is informed about an experimental treatment with only an eight-percent chance of success. This revelation prompts him to reevaluate his life choices and reignite his passion for stand-up comedy.

Meanwhile, aspiring comedian Ira Wright shares an apartment in Los Angeles with his friends Mark and Leo. Mark boasts about his role in a sitcom while navigating his romantic interests.

Mark claims he will step back from pursuing Daisy to give Ira a chance to impress her. This decision complicates the dynamics of their friendship as everyone is entangled in romantic tensions.

At a comedy club, George delivers a darkly humorous routine that catches Ira's attention. Ira later mocks George's performance, setting the stage for a future collaboration.

After George reaches out for help, Ira becomes his assistant, gaining insight into George's serious illness. This role deepens their relationship as Ira supports George during his treatment.

George makes a call to his ex-fiance, Laura, expressing his regrets about their past. He chooses to keep his illness a secret, complicating their emotional reconnection.

Ira discovers that Daisy and Mark have been intimate, leading him to sever ties with her. This revelation adds another layer of complexity to the friendships within the group.

Upon learning about George's illness, Laura visits him, sharing her own struggles with infidelity in her marriage. Their heartfelt reunion allows for the possibility of rebuilding their friendship.

George receives the news that his leukemia is in remission, which brings both relief and new challenges. He realizes he desires a long-term relationship, prompting him to reach out to Laura.

As George navigates his newfound health and feelings for Laura, he struggles to maintain the facade of being ill when Laura's husband unexpectedly arrives. Tensions rise as secrets threaten to unravel.

Laura confronts her husband Clarke about his unfaithfulness, leading to a heartfelt decision about their marriage. This confrontation serves as a turning point for both Laura and George's relationships.

In the aftermath of these events, George reflects on the fallout, including the strain on his friendship with Ira, which ultimately ends due to feelings of betrayal. Both men are left to ponder their life choices.

As Ira returns to his old job and pursues a new relationship with Daisy, he begins to heal from the disappointment with George. His journey reflects the struggles and triumphs of aspiring performers.

The film concludes with George witnessing Ira's newfound confidence on stage, prompting a reconciliation between the two. They share joyful moments of laughter, symbolizing the repair of their friendship amidst life's chaos.