Frankenstein Meets the Wolf Man

Larry was revived when grave robbers stole the wolfsbane that had been buried with him and then the full moon shone on his body. The wolfsbane was the only thing keeping his cursed soul at rest, so without it, the full moon's light triggered his transformation back into the Wolf Man. This explains why he wakes up in the Talbot family crypt with a fatal head wound but still able to move.

Larry becomes the Wolf Man again because the full moon triggers his transformation. Even though he was buried and presumed dead, the curse of the Wolf Man was never lifted. When the grave robbers removed the wolfsbane and the full moon appeared, Larry's body transformed into the Wolf Man and he revived with the fatal head wound still visible on his forehead.

Larry breaks out of the hospital because he knows he will transform into the Wolf Man again during the next full moon and doesn't want to hurt anyone else. After killing a constable during his first transformation, Larry pleaded with Dr. Mannering to summon the police before he could strike again. When the authorities refused to believe his story and restrained him to a bed, Larry bit through his leather bindings and escaped, determined to find a cure for his condition.

Larry frees the Monster because he hopes that by helping find Dr. Frankenstein's notes, he might find a cure for his own curse. When Larry arrives at the Frankenstein estate ruins in Vasaria, he discovers the Monster frozen in ice. He uses a stone to break the ice and release the creature, believing that accessing the legendary Frankenstein notes might be his only hope for relief from his eternal suffering.

Larry's plan is to use Dr. Frankenstein's notes to transfer his life energy to the Monster, effectively giving his life force to the creature so he can finally die. He proposes repairing the old Frankenstein laboratory and using the equipment to drain his life energy and transfer it to the Monster, hoping this exchange will break his cursed cycle of monthly transformations and death.

Dr. Mannering changes the experiment out of scientific curiosity. While Larry intended to transfer his life energy to the Monster and then die, Mannering becomes fascinated by the potential of the Frankenstein equipment and decides to push the procedure further. He modifies the procedure to fully revive the Monster instead of completing the transfer as Larry requested, which leads to disastrous consequences.

When the procedure begins, Mannering starts the machine intending to transfer Larry's life energy to the Monster. However, he becomes curious and pushes the experiment beyond its planned limits, fully reviving the Monster to full strength. The timing coincides with a full moon, which also restores the Wolf Man's strength. The Monster then attacks Elsa Frankenstein, triggering a violent confrontation between the two creatures.

Vazec the innkeeper destroys the dam because he grows suspicious of the conspiracy involving Larry and the Monster and decides to drown everyone at the Frankenstein estate. Believing the creatures and the people experimenting on them are dangerous, Vazec uses dynamite to blow up the dam, hoping the flood will eliminate the threat. His plan succeeds in sweeping both the Wolf Man and the Monster away in the rushing waters.

At the end, both the Wolf Man and the Monster are swept away by the flood caused when Vazec blows up the dam. Elsa escapes with Dr. Mannering, but the two creatures are left caught in the rushing waters as the Frankenstein estate is destroyed. The ending is ambiguous, the monsters are not definitively killed, leaving their fate uncertain as they disappear into the floodwaters.

Earlier in the film, Larry pleads with Mannering to summon the police before he can kill again, establishing his desire to end his curse through death rather than continue living.

Larry helps the Monster escape during the Festival of the New Wine because he sees the creature being attacked by villagers and feels a moment of mercy toward another cursed being. Despite being hunted himself, Larry drives the Monster to safety on a waiting cart. This rare compassionate act shows Larry's underlying humanity, even as he struggles with his own violent transformations.