Doug Kinney, portrayed by Michael Keaton, is a hardworking construction employee based in Los Angeles, who faces continual challenges as his job increasingly intrudes upon his family life. His coworker Vic, played by Eugene Levy, constantly bungles tasks, putting immense pressure on Doug, both financially and emotionally. As a result, Ted Gray, Doug's boss and played by John de Lancie, imposes grueling hours upon him, forcing him to work nights and weekends to rectify Vic's blunders. This leaves little room for Doug to maintain harmony at home or pursue his own interests, as his wife Laura, portrayed by Andie MacDowell, grows frustrated with the situation, yearning to revive her career in real estate.
Amidst the chaos, a significant project surfaces—a new wing for a scientific facility. During this venture, Doug encounters Dr. Leeds, played by Harris Yulin, an amiable scientist who has made groundbreaking strides in human cloning. Kind-hearted and compassionate, Dr. Leeds suggests cloning Doug to alleviate his burdens and permit him to spend more quality time with his family. The clone, initially referred to as "Two" but who prefers to call himself "Lance," possesses all of Doug's memories and knowledge, yet his personality is a hyperbolic manifestation of Doug's more assertive traits.
As Lance steps into Doug's role at work, he quickly proves himself, even going so far as to dismiss Vic for his incompetence. Meanwhile, Doug finds himself inundated with household tasks, as Laura seizes the opportunity to focus on her own career aspirations. Caught in a whirlwind of chores and familial responsibilities, Doug discovers that he has little time to indulge in his personal interests, such as playing golf.
Keeping the existence of his clone secret becomes increasingly complicated, particularly when Doug and Laura go out to dinner. During this outing, Doug is horrified to learn that Lance has gone on a date of his own with a female coworker, leading to a cascade of worries regarding the implications of having a clone who may jeopardize his marriage. Nevertheless, Lance continues to excel in his work, and Doug, in a moment of desperation, decides to create another clone to help manage the increasing demands at home.
Introducing "Three," affectionately dubbed "Rico," establishes the dynamic between the clones further; Rico embodies an exaggerated version of Doug’s feminine side with a nurturing nature and culinary prowess that contrasts sharply with Lance's brash demeanor. Despite their different styles, both clones find a way to befriend each other and complicate Doug's life further by wooing girls while trying to manage domestic duties.
The perfidious progression continues with the creation of "Four," affectionately known as Lenny. This clone, however, is an echo of a lesser version, as his cognitive skills fall short, often resulting in confusion that complicates Doug's life even further. With Lenny muddling things up by referring to Doug as "Steve," Doug finally draws the line, declaring that no more clones should be created.
Tension mounts when Rico unwittingly compromises Doug's surprise plans for a family trip to Disney World, leading for Laura to become increasingly dissatisfied with Doug's unpredictable behavior. Attempting a moment of escapism, Doug opts for a sailing trip, choosing to let his clones handle his responsibilities. However, despite strict instructions to keep out of Laura's path, all three clones end up unintentionally involved with her, each believing they are Doug.
Compounding these troubles, when one clone falls ill, Rico is thrust into work duty, showcasing his lack of knowledge and consequently annoying the inspector. This chain of events leads to Doug losing his job, intensifying the strain on his family life. As misunderstandings spiral out of control, Laura becomes convinced that Doug is neglecting her, sharing her grievances with Lenny, who, unfortunately, misunderstands her requests, only asking for "pizza."
In the aftermath, Doug discovers that his family has left, with Laura taking the children back to her parents, fed up with his erratic moods and careless mistakes. Realizing the gravity of his situation, Doug resolves to assemble the clones for help. Together, they undertake a home renovation project that not only impresses Laura but also rekindles their romance. Doug shares his aspirations of opening his own construction business, leading to the realization that he has gained control over his life.
With emotions resolved and clarity regained, the clones honorably depart to pursue their paths. As they drive away, Laura, still grappling with the notion of multiple Doug clones, catches a glimpse of them, sparking questions about her reality.
Later, the clones—two of whom still embody their exaggerated personalities—send a letter revealing their adventures as successful pizzeria owners in Miami, calling their establishment "Three Guys from Nowhere." While Lance thrives as the businessman, Rico delights in his role as head chef, and Lenny comically struggles as the delivery boy, creating endless laughs as he fumbles his tasks. Doug’s unconventional journey highlights the importance of balance between work and family, laced with humor, heartfelt moments, and the unpredictability of life.
