Madame Web

In 1973, in the depths of the Amazon jungles of Peru, a dedicated research team led by Ezekiel Sims uncovers an unidentified spider species. This creature is noted for its remarkable healing properties, sparking a debate about its potential medical applications and the pursuit of superhuman abilities.

Cassandra Webb, one of Ezekiel's colleagues, becomes fascinated with the spider's venom for its potential to cure ailments. Meanwhile, Ezekiel's focus shifts to the possibility of using the spider's properties for enhancing human strength, showcasing their differing priorities during the research.

As the team conducts their research, a struggle ensues over the prized spider. In a shocking betrayal, Ezekiel shoots Cassandra during the chaos, leaving her to die alone after a local tribe attempts to save her with a spider bite.

After being bitten by the spider, Cassandra tragically dies shortly after giving birth to her daughter, Cassie. This event sets into motion a legacy filled with danger and supernatural connections that will haunt Cassie throughout her life.

Fast forward thirty years, and Cassie lives in New York City, working as a paramedic alongside her coworkers Ben and O'Neil. Orphaned at a young age, she carries her mother's research notes, which she cannot fully comprehend, hinting at her uncertain heritage.

While responding to an emergency call involving a flipped car, Cassie experiences a life-threatening situation that leads to a near-death experience. After being revived by her colleague Ben, she begins to have unsettling visions that hint at her latent abilities.

During a call to a fire at an industrial facility, Cassie foresees a tragic event where she fails to save O'Neil. When this vision comes true and results in O'Neil's death, Cassie becomes painfully aware of her ability to predict future events.

Meanwhile, Ezekiel, now endowed with limited precognitive abilities, hunts three girls whom he believes will become Spider-Woman. Using advanced tracking tools, he is determined to eliminate them before they can fulfill their perceived fate.

Cassie's journey intersects with the girls when they unexpectedly meet in a train carriage. Sensing danger, she recognizes the threat posed by Ezekiel, compelling her to take quick action to protect them from imminent harm.

In a dramatic showdown at Grand Central Terminal, a fueled Ezekiel attacks Cassie and the girls while donning a black Spider-Man suit. Cassie musters her courage, commandeering a taxi, and escapes the city to keep the girls safe.

Back in her apartment, Cassie reviews her mother's research and unravels the mysteries surrounding Ezekiel's powers that stem from the spider's venom. She learns that her mother’s intentions were not selfish but aimed at protecting Cassie from a hereditary affliction.

When Cassie's decision to let the girls venture to a diner leads to their exposure to Ezekiel, it becomes a critical moment. Realizing that time is of the essence, Cassie races against the clock to rescue them from the clutches of their pursuer.

In a heart-pounding chase back to Queens, Cassie and the girls seek refuge in Ben's home. As the threat escalates, Cassie teaches the girls essential survival skills to empower them against Ezekiel's advances.

To confront the past, Cassie embarks on a journey back to Peru, seeking the tribal chief who saved her mother. Undergoing a pivotal ritual, she discovers profound truths about life’s connections and her own purpose.

In a climactic encounter, Cassie plans a trap for Ezekiel while ensuring the safety of Mary, who goes into labor unexpectedly. Despite her injuries, Cassie’s newfound visions of the future help her emerge as a hero destined to mentor the next generation.